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All _____ consist of a thiazolidine ring, a beta-lactam ring, and an R group.


A) penicillins
B) tetracyclines
C) macrolides
D) cephalosporins
E) aminoglycosides

F) B) and D)
G) B) and C)

Correct Answer

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Species of Bacillus produce bacitracin and the polymyxin drugs.

A) True
B) False

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An antibiotic of the penicillin family is penicillin G.

A) True
B) False

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A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions. This is called the ______.


A) Kirby-Bauer technique
B) antibiogram
C) E-test
D) minimum inhibitory concentration (MIC)
E) therapeutic index (TI)

F) All of the above
G) B) and C)

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The use of a drug to prevent imminent infection is called ______.


A) competitive inhibition
B) synergism
C) prebiotics
D) prophylaxis
E) lantibiotics

F) None of the above
G) A) and B)

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The drug used against intestinal anaerobic bacteria, that can also alter normal biota leading to antibiotic-associated colitis, is ______.


A) chloramphenicol
B) clindamycin
C) ciprofloxacin
D) bacitracin
E) gentamicin

F) A) and E)
G) All of the above

Correct Answer

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The drug used for several protozoan infections is ______.


A) nystatin
B) griseofulvin
C) amphotericin B
D) sulfa drugs
E) metronidazole

F) A) and B)
G) B) and C)

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You have given a dosage of an antibiotic to a patient for his infection, but the patient is not getting any better. The MIC tests shows that the drug that you prescribed, at the dosage that was given, should work against this particular strain of bacterium. What do you think might be the problem?


A) The drug might be broken down in the patient's body before it can have its full effect on the bacterium.
B) The patient is resistant to the drug.
C) The bacterium is immune to the chemical effects of the drug.
D) The drug was improperly made at the pharmaceutical company, so is no longer effective.

E) A) and D)
F) B) and C)

Correct Answer

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Who is considered to be the father of modern antibiotics?


A) Watson
B) Fleming
C) Crick
D) Chargaff
E) Domagk

F) None of the above
G) B) and D)

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Which antimicrobial does not interfere with protein synthesis?


A) Aminoglycosides
B) Tetracyclines
C) Erythromycin
D) Trimethroprim
E) Chloramphenicol

F) C) and D)
G) B) and E)

Correct Answer

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Selective toxicity should be avoided when developing a new antimicrobial drug.

A) True
B) False

Correct Answer

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Primaquine and chloroquine are drugs used in the treatment of ______ infections.


A) gram-positive bacterial
B) gram-negative bacterial
C) fungal
D) protozoan
E) viral

F) A) and D)
G) C) and E)

Correct Answer

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A major source of naturally produced penicillin is the mold ______.


A) Penicillium notatum
B) Penicillium chrysogenum
C) Penicillium familiaris
D) Naturally produced penicillin is no longer used.

E) B) and C)
F) A) and B)

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Drug toxicity occurs when an antimicrobial drug acts as antigen and stimulates an allergic response.

A) True
B) False

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The use of any chemical in the treatment, relief, or prophylaxis of a disease is called ______.


A) prophylaxis
B) chemotherapy
C) selective toxicity
D) nephrotoxicity
E) synergism

F) C) and D)
G) B) and C)

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The first modern antimicrobial drugs were sulfa drugs.

A) True
B) False

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Each of the following target bacterial ribosomes, except ______.


A) streptomycin
B) gentamycin
C) polymyxins
D) tetracycline
E) erythromycin

F) A) and C)
G) None of the above

Correct Answer

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Which drug is used to treat cases of tuberculosis?


A) Penicillin G
B) Vancomycin
C) Tetracycline
D) Synercid
E) Isoniazid

F) C) and E)
G) A) and C)

Correct Answer

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Acyclovir is used to treat infections caused by ______.


A) influenza A virus
B) HIV
C) herpes simplex virus
D) respiratory syncytial virus
E) hepatitis C virus

F) A) and E)
G) A) and C)

Correct Answer

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Which of the following is not used to treat malaria?


A) Quinine
B) Chloroquine
C) Metronidazole
D) Primaquine
E) Me?aquine

F) B) and D)
G) C) and E)

Correct Answer

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