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T-cell receptors will bind with their specific antigens


A) immediately upon encountering them.
B) when presented by an antigen-presenting cell.
C) after antibodies are produced for that antigen.
D) either immediately upon encountering them or when presented by an APC.
E) only in the presence of histamine.

F) A) and E)
G) A) and D)

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If a person has a genetic defect in the metabolic pathway that produces cytokines, then


A) macrophages will not be produced by the immune system.
B) B cells would not be activated to respond when cells presenting antigens are present.
C) helper T cells would take over the role of activating B cells.
D) the spleen would destroy all red blood cells.
E) histamine will not be produced by mast cells.

F) B) and E)
G) D) and E)

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Neutrophils and macrophages are different in that


A) neutrophils produce antibodies, while macrophages do not.
B) neutrophils produce histamines, while macrophages produce antibodies.
C) neutrophils travel to the site of injury, while macrophages reside in certain tissues.
D) neutrophils phagocytize pathogens, while macrophages produce holes in a pathogen's membrane.
E) neutrophils are part of the inflammatory response, while macrophages are not.

F) B) and E)
G) B) and D)

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Which statement about vaccines is correct?


A) Vaccines will always cause the patient to become ill in order to build the immune system.
B) Vaccines never cause the patient to become ill in order to build the immune system.
C) Vaccines are not intended to cause the patient to become ill in order to build the immune system.
D) Vaccines need to be administered on a continuous basis in order to be effective.
E) It is only necessary to be vaccinated once in order to have immunity for your entire life.

F) B) and C)
G) A) and E)

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Which of the following is not correct in describing the spleen?


A) It contains red pulp and white pulp.
B) It is an essential organ for survival.
C) It can be involved in fighting cancer.
D) It is spongy, containing many sinuses.
E) It is easily ruptured by a severe blow or infection.

F) C) and D)
G) A) and D)

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T lymphocytes


A) migrate from the thymus to the bone marrow where they mature.
B) that recognize "self-cells" leave the thymus and enter lymphatic vessels and organs.
C) must have the antigen presented to them by an antigen-presenting cell.
D) develop into plasma cells once activated.
E) are a component of the body's nonspecific immune defenses.

F) B) and D)
G) D) and E)

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Which of the following is not an autoimmune disease?


A) myasthenia gravis
B) rheumatoid arthritis
C) multiple sclerosis
D) systemic lupus erythematosus
E) tuberculosis

F) A) and C)
G) B) and D)

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During tissue transplant, what is the main reason for the rejection of the transplanted tissue?


A) Cytotoxic T cells and antibodies in the body destroy the transplanted tissue.
B) Helper T cells and antibodies in the body destroy the transplanted tissue.
C) Cytotoxic T cells and antibodies will reroute the blood supply away from the transplanted tissue, starving it to death.
D) The host body's antigens will not allow the transplanted tissue to attach to the host.
E) The host body red blood cells will not carry oxygen to the transplanted tissue.

F) B) and C)
G) C) and D)

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Natural killer cells can destroy cancer cells that have lost their "self" proteins.

A) True
B) False

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When people are hypersensitive to pollen, they have _____ in response to the antigens on pollen called _____.


A) an autoimmune disease; cytokines
B) immunity; allergens
C) an allergy; allergens
D) an allergy; IgG
E) immunity; antibodies

F) A) and D)
G) D) and E)

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Which body system plays the greatest role in fighting cancer?


A) immune system
B) cardiovascular system
C) neural system
D) digestive system
E) integumentary system

F) B) and E)
G) C) and D)

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When a disease has been fought off by the immune system, what happens to the leftover cells that were produced by the immune system to fight the disease?


A) Apoptosis occurs.
B) They are saved for later use.
C) They are stored in the thymus gland.
D) They are destroyed by bone marrow.
E) They are killed by cytotoxic T cells.

F) A) and B)
G) All of the above

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Which substances are examples of antigens?


A) proteins and carbohydrates
B) nucleic acids and proteins
C) lipids and proteins
D) lipids and carbohydrates
E) nucleic acids and carbohydrates

F) A) and D)
G) None of the above

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Which of the following is not an autoimmune disease?


A) AIDS
B) myasthenia gravis
C) multiple sclerosis
D) systemic lupus erythematosus
E) rheumatoid arthritis

F) C) and D)
G) B) and C)

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Which of the following statements is not true regarding the complement proteins?


A) They are blood plasma proteins.
B) Some form the membrane attack complex, which forms a hole in the bacterial plasma membrane.
C) They may amplify the inflammatory response by attracting phagocytes to the site of the infection.
D) They may bind to pathogens already coated with antibodies, ensuring they are phagocytized.
E) Many proteins must be independently activated in order to have a significant impact on the immune response.

F) D) and E)
G) B) and C)

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Which cell type plays a role in adaptive immunity in the body?


A) lymphocytes
B) red blood cells
C) platelets
D) epithelial cells
E) None of these cell types play a role in adaptive immunity.

F) None of the above
G) B) and D)

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T lymphocytes mature in the


A) thyroid gland.
B) bone marrow.
C) thymus.
D) spleen.
E) blood.

F) A) and C)
G) A) and E)

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A person has type A blood. This means that


A) she has A antigens on her red blood cells and can only receive type A blood in transfusions.
B) she produces A antibodies when type A blood is used in transfusion, causing agglutination.
C) she has A antigens on her red blood cells and will produce antibodies if red blood cells with B antigens are transfused into her body.
D) she has B antigens on her red blood cells and can only receive type O blood.
E) she produces A antibodies when type B blood is used in a transfusion.

F) None of the above
G) A) and E)

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_____ cells kill virus-infected cells and tumor cells by cell-to-cell contact.


A) Natural killer
B) Plasma
C) Cytotoxic T
D) Memory B
E) Helper T

F) A) and E)
G) B) and D)

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This is a graph of antibodies in an immunized person's blood. At point B _____ is given that enhances the immunity to the pathogen. This is a graph of antibodies in an immunized person's blood. At point B _____ is given that enhances the immunity to the pathogen.   A)  a booster B)  the primary exposure to the vaccine C)  a dose of antibodies D)  a live pathogen E)  histamine


A) a booster
B) the primary exposure to the vaccine
C) a dose of antibodies
D) a live pathogen
E) histamine

F) A) and D)
G) A) and C)

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